inflammatory bowel disease
Conditions
Interventions
MDT decision-making group:MDT decision-making
Non-MDT decision-making group:Non-MDT decision-making
Retrospective section: IBD patients:NA
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Retrospective study inclusion criteria: (1) According to the Consensus on Diagnosis and Treatment of Inflammatory Bowel Disease in China (2018, Beijing), patients clinically diagnosed with UC or CD (2) capable of independently signing an informed consent form (3) aged between 18-80 years, regardless of gender. Inclusion criteria for the randomized controlled part :(1) According to the Chinese consensus Opinion on the Diagnosis and Treatment of inflammatory bowel Disease (2018 · Beijing) (" Consensus "), patients with clinical diagnosis of CD :(2) aged 16-80 years, male or female; (3) Consistent with the diagnosis of intestinal stenosis :a. The presence of definite clinical manifestations of intestinal obstruction without neoplastic stenosis; B-imaging, ultrasound or endoscopy: intestinal ultrasound /CT to measure intestinal wall thickness > 4mm, and the diameter of the stenosed upper segment of the bowel > 3cm; The simplified endoscopy for Crohn's disease (SES-CD) score was "stenosis"; The colonoscopy could not pass through; c Pathology: surgical pathology suggested submucosal and/or lamina propria fibrosis: or biopsy pathology could fully observe submucosa, there was submucosal fibrosis.
Exclusion criteria
Exclusion criteria: (1) Failure to provide informed consent (2) Simultaneous presence of additional autoimmune disorders or malignant tumors within the gastrointestinal system. Exclusion criteria for the control group: a. Failure to provide informed consent. b. Coexistence of other autoimmune diseases or gastrointestinal malignancies. c. Pregnant individuals or those with contraindications for intestinal surgery. Inclusion criteria for the randomized controlled part :(1) Refusal to sign informed consent :(2) pregnant women with other autoimmune diseases or malignant tumors of the digestive tract :(3) inappropriate use of biological agents or surgery; (4) refusing to attend the consultation of enteropathy in Peking Union Medical College Hospital.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of treatment at 12 months after treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of major clinical events among patients; | — |
Countries
China
Contacts
Public ContactHong Yang
Peking Union Medical College Hospital
Outcome results
None listed