Evaluation value of depleted T lymphocytes combined with mitochondrial function impairment in prognosis of ICU sepsis patients

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300076772

Enrollment

Unknown

Registered

2023-10-18

Start date

2023-11-01

Completion date

Unknown

Last updated

2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Healthy control group:Nil

Sepsis non shock group:Nil

Sepsis shock group:Nil

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years; 2.Sepsis patients were diagnosed according to sepsis 3.0 diagnostic criteria issued by the American Medical Association. Diagnostic criteria of sepsis: Patients with severe infection and organ dysfunction, and SOFA score >= 2.

Exclusion criteria

Exclusion criteria: ? Patients with a history of chronic cardiac insufficiency; ? Patients with a history of malignant tumor; ? Patients with previous history of organ transplantation; ? Patients with previous immune deficiency; Age 90 years old; The expected length of ICU stay is less than 24h

Design outcomes

Primary

Measure	Time frame
T lymphocyte count;Percentage of CD3+CD4+PD1+ T cells;Percentage of CD3+CD8+PD1+ T cells;Mitochondrial low membrane potential ratio;	—

Countries

china

Contacts

Public ContactYun Zhao

Yizheng Hospital ,Nanjing Drum Tower Hospital Group

12932232@qq.com+86 514 8085 6342

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026