Effect of inhaled hydrogen on acute kidney injury after laparoscopic partial nephrectomy

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300076767

Enrollment

Unknown

Registered

2023-10-18

Start date

2023-11-01

Completion date

Unknown

Last updated

2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative renal function

Interventions

C group:Inhalation of 66.7% air+33.3% oxygen

H group:Inhalation of 66.7% hydrogen+33.3% oxygen

Eligibility

Sex/Gender

All

Age

50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) Age 50-70 years old; 2) ASA grading I-III; 3)BMI 18-30kg/m2; 4) Laparoscopic unilateral partial renal resection surgery.

Exclusion criteria

Exclusion criteria: 1) Emergency surgery; 2) expected length of hospital stay 140mmHg or DP>90mmHg); 8) Intraoperative blood pressure instability requires high-dose vasoactive drugs or blood transfusion; 9) Renal artery occlusion time > 30min during partial nephrectomy.

Design outcomes

Primary

Measure	Time frame
The incidence of postoperative acute kidney injury;	—

Secondary

Measure	Time frame
Inflammatory indicators: IL-6 and TNF in the blood- a IL-18 level;Time from extubation to complete awakening after surgery;Postoperative nausea, vomiting, delirium, drainage tube removal time, hospital stay;Postoperative pain score and patient PCA usage;	—

Countries

China

Contacts

Public ContactChangjun Gao

Tangdu Hospital, Air Force Military Medical University

gaocj74@163.com+86 29 8477 7439

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026