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Molecular-Imaging Mechanisms for Acupuncture in Acute Ischemic Stroke Based on 1H-MRS

Molecular-Imaging Mechanisms for Acupuncture in Acute Ischemic Stroke Based on 1H-MRS

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076763
Enrollment
Unknown
Registered
2023-10-18
Start date
2023-10-19
Completion date
Unknown
Last updated
2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute ischemic stroke

Interventions

A:acupuncture by Shengyang Tongdu
B:point bloodletting by Jing-well point
C:scalp acupuncture

Sponsors

Yunnan Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed with unilateral hemispheric infarction and onset it within 1 month, accompanied by motor dysfunction of one side of the limb;2. Aged from 35 to 75, male or female;3. Conscious, no dementia, no aphasia, no mental disorders, can maintain the basic sitting and head balance, and with the examination and treatment;4. Signed the informed consent form by oneself or by his immediate family members;5. No treatment by acupuncture within 24 hours; 6. Meet the diagnostic standards of Chinese and Western medicine; 7. Right-handed.

Exclusion criteria

Exclusion criteria: 1. Examination confirmed the neurological defects caused by brain tumors, brain trauma, cerebral hemorrhage, cerebral parasitic disease, and other diseases;2. Diagnosed with transient ischemic attack, reversible neurological impairment, and other patients;3. Having undergone thrombolytic therapy, or those with large vessel occlusion after thrombectomy; 4. Confirmed the serious diseases involving the heart, lung, liver, kidney, and other organs, and hearing or visual impairment; 5. Existing hand and foot insufficiency; 6. unstable condition and unadhered and uncooperative treatment;7. Having cardiac pacemakers, stent placement, after bypass surgery, and other fMRI tests contraindications; 8. Partial brain deficit before the recurrent stroke; 9. Acupuncture skin allergy or intolerance, skin infection, claustrophobia;10. Participating in other clinical trials, and do not agree to sign the informed consent.

Design outcomes

Primary

MeasureTime frame
The imaging by 1H-MRS;SOD;MDA;LPO;CK-MB;LDH;LDL;

Secondary

MeasureTime frame
the NIHSS score;the mRS score;the Symptom with Chinese Medicine score;

Countries

China

Contacts

Public ContactShi Jing

Yunnan Provincial Hospital of Traditional Chinese Medicine

2662831291@qq.com+86 130 0869 6896

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026