portal hypertension
Conditions
Interventions
Case series:None
Sponsors
Henan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-65 years with cirrhosis and portal hypertension 2. To evaluate the efficacy of drugs for primary and secondary prevention of esophageal and gastric variceal bleeding 3. To predict the bleeding risk of esophageal and gastric varices and to guide the selection of treatment 4. To predict the risk, progression and clinical prognosis of decompensation events in cirrhosis 5. Evaluate the efficacy of related new drugs 6. Evaluate the accuracy of the relevant non-innovative technology 7. Diagnosis and differential diagnosis of portal hypertension types
Exclusion criteria
Exclusion criteria: 1. Child-Pugh classification of liver function >B 2. Abdominal water volume >1000ml/ Platelet 2mg/dL or 177mmol/L), or abnormal liver function (ALT>2 times the upper limit of normal). Moderate to severe chronic obstructive pulmonary disease/ Patients with severe hypertension and cerebrovascular accidents 6. Suffering from serious organic diseases, such as cancer, coronary heart disease, myocardial infarction and stroke 7. Suffering from infectious diseases such as tuberculosis and AIDS 8. There is a mental illness, communication barriers and no capacity for civil conduct
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| portal venous pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| internal diameter of main portal vein and its branches;velocity of main portal vein and its branches; | — |
Countries
China
Contacts
Public ContactLianzhong Zhang
Henan Provincial People's Hospital
Outcome results
None listed