Emergence delirium
Conditions
Interventions
DEX group:Patients were premedicated with intranasal dexmedetomidine 2 µg/kg
ESK group:Patients were premedicated with intranasal esketamine 1 mg/kg.
DEX-ESK group:Patients were premedicated with intranasal dexmedetomidine1 µg/kg plus esketamine 0.5 mg/kg.
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 5 Years
Inclusion criteria
Inclusion criteria: 1. ASA physical status I or II; 2. Aged 2-5 years; 3. Scheduled for elective tonsillectomy.
Exclusion criteria
Exclusion criteria: 1. Parents refusing to allow their children to participate; 2. Intake of sedative or analgesic medication within 48 hours before surgery; 3. Physical or developmental delay; 4. Psychosis; 5. Body mass index > 30 kg/m2; 6. Allergy to study drugs; 7. Major life changes 1 month before the operation, such as the divorce of parents, death of parents, moving to a new home, changing to a new kindergarten, etc.; 8. Any other conditions that precluded study inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of emergence delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative negative behavior changes;Length of postanesthesia care unit stay;Emergence time;Parental satisfaction;Postoperative pain intensity;Sedation level;Reaction to parental separation; | — |
Countries
China
Contacts
Public ContactYao Yusheng
Fujian Provincial Hospital
Outcome results
None listed