postoperative chronic pain
Conditions
Interventions
Experimental group:Paraspinal nerve block combined with dexmedetomidine as adjuvant
Control group:Paraspinal nerve block
Sponsors
Second Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: The age ranged from 18 to 75; American Society of Anesthesiologists (ASA) Ratings I-II; Patients undergoing elective thoracoscopic lobectomy; All surgeries were performed by the same surgical physician team. Patients who agreed to participate in the study and signed informed consent for anesthesia.
Exclusion criteria
Exclusion criteria: Refuse PVB blockade;severe cardiovascular diseases,EF<40%; severe pulmonary diseases (FEV1/FVC<40%); liver and kidney dysfunction; chronic cough and phlegm such as chronic bronchitis and COPD; chronic pain; puncture point infections;history of chest surgery and chest trauma;history of neurological diseases;opioid abuse;persistent and recurrent cancer pain;refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative chronic pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score of postoperative chronic pain severity;Neuropathic pain ID score;Quality of Life SF-12 score;NRS scores at 4, 24 and 48 hours postoperatively;Postoperative first out-of-bed activity time;Incidence of postoperative nausea and vomiting;Plasma levels of TNF,IL-6,IL-1; | — |
Countries
China
Contacts
Public ContactZhang ling wei
Second Affiliated Hospital of Soochow University
Outcome results
None listed