Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) It meets the diagnostic criteria of degenerative arthropathy: A. Diagnostic criteria for Western medicine ? Age = 50 years old; ? Morning stiffness < 30 min; ? Knee examination indicates bone hypertrophy; ? There is bone noise during joint movement; ? Bone tenderness; ? Radiological examination showed osteophyte formation; ? No obvious synovial temperature rise. Patients with 3 of the above 7 items were diagnosed as knee osteoarthritis. B. Diagnostic criteria of traditional Chinese medicine (according to the Criteria for the Diagnosis and Curative Effect of Traditional Chinese Medicine issued by the State Administration of Traditional Chinese Medicine and the Guiding Principles for Clinical Research of New Chinese Medicines issued by the Ministry of Health); ? At the beginning, it is common to see faint pain in the knee joint. During the activity, the joint can not smoothly complete the flexion and extension movement, and the completion of the lateral movement is also poor. The pain can be slightly relieved after rest or slight activity, and it will recur when the temperature drops, which is difficult to recover for a long time; ? Local swelling of the knee joint is not difficult to be found. During movement, you can hear bone frictions between joints or have obvious bone friction feeling. In severe cases, you can see obvious joint deformities; ? The onset of disease is slow, and the middle-aged and elderly are more common; ? Osteoporosis exists. The X-ray film can show the narrowing of joint space, the hyperplasia of subchondral bone, and the formation of osteophytes; ? There was no abnormality in ESR and anti-O, and no abnormal rheumatoid factor and mucin were detected. (2) Patients who voluntarily participated in this randomized controlled trial and signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Knee patients with central and peripheral nerve injury. (2) BMI index = 28 (3) Mitochondrial myopathy, periodic paralysis and other primary muscle diseases (4) Severe renal or parathyroid dysfunction (5) Those with mental disorders who cannot cooperate with treatment or examination (6) Pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC score;Quadriceps femoris contraction efficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Range of motion(ROM); | — |
Countries
China
Contacts
the first affiliated hospital, Sun yat-sen University