Pulmonary Vein Isolation With and Without Posterior Wall Isolation in Persistent Atrial Fibrillation

Randomized Controlled Study on the Efficacy and safety of Pulmonary Vein Isolation With and Without Posterior Wall Isolation in Persistent Atrial Fibrillation

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300076635

Enrollment

Unknown

Registered

2023-10-13

Start date

2023-10-15

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Persistent Ayrial Fibrillation

Interventions

Pulmonary Vein Isolation Group:Pulmonary Vein Isolation

Pulmonary Vein Isolation(PVI) with Posterior Wall Isolation:PVI with Posterior Wall Isolation

electrophysiological test group:Atrial Fibrillation With a Left Atrial Low-Voltage Area underwent PVI+PWI

Atrial Fibrillation Without a Left Atrial Low-Voltage Area but ERP=180 ms underwent PVI+PWI

Atrial Fibrillation Without a Left Atrial Low-Voltage Area but ERP>180 ms underwent PVI.

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? Patients aged = 18 years old. ? Patients with persistent atrial fibrillation who comply with official guidelines,with a duration of atrial fibrillation of = 7 days and an electrocardiogram of atrial fibrillation. ? patients are able to sign an informed consent form and agree to participate in this study. ? Patients are able to comply with all research follow-up requirements.

Exclusion criteria

Exclusion criteria: ? Patients with valvular atrial fibrillation. ? The duration of atrial fibrillation is more than 3 years. ? Left atrial diameter = 45mm. ? With hypertrophic cardiomyopathy. ? Secondary atrial fibrillation caused by other diseases which can be corrected, such as hyperthyroidism. ? Those who have contraindications for using anticoagulants. ? Severe renal or liver failure.

Design outcomes

Primary

Measure	Time frame
The incidence of no atrial arrhythmias greater than 30 seconds;No use of antiarrhythmic drugs and no occurrence of atrial tachycardia/flutter exceeding 30 seconds;	—

Secondary

Measure	Time frame
No use of antiarrhythmic drugs and no occurrence of atrial fibrillation exceeding 30 seconds;Atrial fibrillation load;Ablation time and surgical time;Perioperative complications;	—

Countries

China

Contacts

Public ContactHao Jie

The Second Hospital of Hebei Medical Uniesity.

haojiemed@163.com+86 138 3310 0706

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026