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Effects of combined multimodal exercise and cognitive training on cognitive function in older adults with mild dementia: a randomized controlled trial

Effects of combined multimodal exercise and cognitive training on cognitive function in older adults with mild dementia: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076623
Enrollment
Unknown
Registered
2023-10-13
Start date
2023-03-06
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementia

Interventions

Sponsors

The University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. The inclusion criteria of dementia subjects are: (1) Aged >= 60 years; (2) Have a diagnosis of dementia (AD, vascular dementia, or other types of dementia) based on the Diagnostic and Statistical Manual of Mental Disorders-5th edition (DSM-V) or the International Statistical Classification of Diseases and Related Health Problems-10th Revision (ICD-10); (3) Clinical Dementia Rating Scale (CDR) = 1, indicating mild dementia; (4) Can participate in exercise interventions assessed by the Physical Activity Readiness Questionnaire for Everyone (PAR-Q+); (5) Be literate and have the ability to read and write Chinese; (6) Have a family caregiver willing to participate. 2. The inclusion criteria of family caregivers are: (1) Aged >= 18 years; (2) Co-residing with PwD; (3) Be literate and have the ability to read and write Chinese; (4) Have an electronic device with internet access, and have the ability to use technology; (5) Cognitively intact.

Exclusion criteria

Exclusion criteria: The exclusion of dementia subjects are: (1) Having any absolute or relative contraindications of exercise according to the American College of Sports Medicine (ACSM); (2) With active psychiatric disorders requiring treatments or obvious behavioral and psychological symptoms of dementia which may preclude subjects following the intervention instructions; (3) With hearing or vision impairment that preventing subjects from answering questionnaires and engaging in the intervention; (4) Have a regular exercise training for more than 150 min per week or currently participating in any interventions that aim to improve cognition; (5) Are incompetent in giving consent.

Design outcomes

Primary

MeasureTime frame
Global cognitive function;

Secondary

MeasureTime frame
Response inhibition and attention;Cognitive shifting, attention, and processing speed;Working memory and attention;Memory;Neuropsychiatric symptom;Instrumental activities of daily living;Quality of life;

Countries

China

Contacts

Public ContactDandan Xue

The University of Hong Kong

u3007482@connect.hku.hk+852 5172 2854

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026