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A Traverse Cohort Study of Genetic Basis for Language and Reading Development Disability in Chinese Primary School Students aged 6-12

A Traverse Cohort Study of Genetic Basis for Language and Reading Development Disability in Chinese Primary School Students aged 6-12

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076610
Enrollment
Unknown
Registered
2023-10-12
Start date
2023-10-31
Completion date
Unknown
Last updated
2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reading disability, dyslexia

Interventions

Reading disability, dyslexia:None

Sponsors

Shenzhen Institute of Neuroscience
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Age 6-12 years old, primary school students; 2. The ratio of male to female is 1:1; 3. Normal intelligence, Webster Intelligence Test IQ = 80; 4. Normal vision or corrected vision or hearing; 5. Native speakers of Chinese; 6. Right-handed.

Exclusion criteria

Exclusion criteria: 1. Have serious physical diseases (such as cardiovascular, cerebrovascular, liver and kidney diseases, etc.); 2. Have obsessive-compulsive disorder, Tourette syndrome, depression, autism, attention deficit hyperactivity disorder, severe emotional disorder, or any other neurological disorder, with a family history of mental illness.

Design outcomes

Primary

MeasureTime frame
Whole genome sequencing detection and analysis;DNA methylation detection and analysis;Non targeted metabolome detection and analysis;16S Microbial Detection and Analysis;

Secondary

MeasureTime frame
Standardized Test Score for Chinese Reading Ability;Edinburgh Handedness Assessment Scale;Language history questionnaire (LHQ 3.0);Family cultural environment survey questionnaire;

Countries

China

Contacts

Public ContactLi-Hai Tan

Shenzhen Institute of Neuroscience

tanlh@sions.cn+86 136 3269 2317

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026