meconium aspiration syndrome
Conditions
Interventions
the treatment group:the treatment group was given 2ml of budesonide for treatment
The control group:The control group was given 2ml of normal saline for treatment,
Sponsors
Huai'an Maternity and Child Healthcare Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) Full-term infants with meconium in the amniotic fluid; weight = 2.5 kg; (2) meconium could be detected or aspirated below the vocal cords following endotracheal intubation; (3) respiratory distress started within 6 h of birth; (4) signs of infiltration, hyperinflation or atelectasis by chest x-ray examination; (5) other possible causes of neonatal respiratory distress were excluded.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) Premature or small for gestational age; (2) severe congenital malformation; (3) parents were unwilling to participate in the study; (4) neonates that died within 24 h or abandoned treatment. Guardians of all neonates included were informed and signed informed consent forms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation index;length of oxygen inhalation;Total Oxidant State of Serum ;total antioxidant capacity;Oxidative stress index; | — |
Secondary
| Measure | Time frame |
|---|---|
| mortality;length of mechanical ventilation; | — |
Countries
China
Contacts
Public ContactZhaojun Pan
Huai'an Maternity and Child Healthcare Hospital
Outcome results
None listed