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the role of glial cell-derived neurotrophic factors in cancer pain and depression

The role of GDNF in cancer induced pain and depression

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076591
Enrollment
Unknown
Registered
2023-10-12
Start date
2023-10-15
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer pain and depression

Interventions

Cancer pain with depression group:none
Healthy controls group:none

Sponsors

Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Patients are aged 40-70 years, 2.Pathological diagnosis in patients with malignant tumors and/or Whole-body bone scan confirms bone metastases, 3.The duration of cancer pain = 3 months and VAS pain score = 4, 4.Hamilton Depression Scale = 8.

Exclusion criteria

Exclusion criteria: 1.Combined with severe cardiopulmonary disease, severe liver and kidney function impairment, severe anemia and neurological diseases, 2.VAS pain score < 4.

Design outcomes

Primary

MeasureTime frame
GDNF;—

Secondary

MeasureTime frame
IL-6;il-10;TNF-a;—

Countries

China

Contacts

Public ContactSong Zongbin

Xiangya Hospital of Central South University

songzb2001@163.com+86 137 8724 6060

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026