diaphragm dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients scheduled for elective lobectomy at our institution: 1. ASA class I-III; 2. Preoperative ultrasound showed normal diaphragm excursion: 9 mm for women and 10 mm for men; 3. Patients who underwent unilateral lobectomy at our institution and who had been on mechanical ventilation for longer than 1 h; 4. Age greater than or equal to 18 years old; 5. No preoperative radiotherapy, chemotherapy, or any other treatments that might have affected the diaphragm's function.
Exclusion criteria
Exclusion criteria: 1, suffering from myasthenia gravis, myasthenia gravis syndrome, periodic paralysis, polymyositis and other neuromuscular disease history; 2, previous thoracic surgery history; 3, BMI>35; 4, postoperative subcutaneous emphysema significantly affecting the examination; 5, the anterior thoracic area with a large burn scar or previous chest wounds, radical mastectomy and other imaging lung ultrasonography results; 6. The preoperative cardiac function classification is greater than or equal to grade III, or the combination of serious heart, cerebrovascular disease, liver and renal function damage, neuropsychiatric disease, dementia, psychological disease, etc.; 7. Difficulty in intubation or difficult airway; 8. Patients and their family members refused to sign the written informed consent; 9. Patients who could not cooperate with the experiment due to combined psychiatric history and cognitive dysfunction. 10. Intraoperative thoracic adhesion severe accumulation of phrenic nerve (informed by the surgeon intraoperatively)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diaphragm excursion;diaphragm volume;diaphragm densities;Diaphragmatic vault height; | — |
Secondary
| Measure | Time frame |
|---|---|
| hypoxemia;inflammation of the lungs; | — |
Countries
China
Contacts
Affiliated Hospital of Southwest Medical University