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CT assessment of diaphragmatic function in patients undergoing thoracic surgery: comparison with ultrasound and prognostic implications

CT assessment of diaphragmatic function in patients undergoing thoracic surgery: comparison with ultrasound and prognostic implications

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076570
Enrollment
Unknown
Registered
2023-10-12
Start date
2023-10-12
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diaphragm dysfunction

Interventions

Trail group:None

Sponsors

Affiliated Hospital of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients scheduled for elective lobectomy at our institution: 1. ASA class I-III; 2. Preoperative ultrasound showed normal diaphragm excursion: 9 mm for women and 10 mm for men; 3. Patients who underwent unilateral lobectomy at our institution and who had been on mechanical ventilation for longer than 1 h; 4. Age greater than or equal to 18 years old; 5. No preoperative radiotherapy, chemotherapy, or any other treatments that might have affected the diaphragm's function.

Exclusion criteria

Exclusion criteria: 1, suffering from myasthenia gravis, myasthenia gravis syndrome, periodic paralysis, polymyositis and other neuromuscular disease history; 2, previous thoracic surgery history; 3, BMI>35; 4, postoperative subcutaneous emphysema significantly affecting the examination; 5, the anterior thoracic area with a large burn scar or previous chest wounds, radical mastectomy and other imaging lung ultrasonography results; 6. The preoperative cardiac function classification is greater than or equal to grade III, or the combination of serious heart, cerebrovascular disease, liver and renal function damage, neuropsychiatric disease, dementia, psychological disease, etc.; 7. Difficulty in intubation or difficult airway; 8. Patients and their family members refused to sign the written informed consent; 9. Patients who could not cooperate with the experiment due to combined psychiatric history and cognitive dysfunction. 10. Intraoperative thoracic adhesion severe accumulation of phrenic nerve (informed by the surgeon intraoperatively)

Design outcomes

Primary

MeasureTime frame
diaphragm excursion;diaphragm volume;diaphragm densities;Diaphragmatic vault height;

Secondary

MeasureTime frame
hypoxemia;inflammation of the lungs;

Countries

China

Contacts

Public ContactLi Liu

Affiliated Hospital of Southwest Medical University

niuniudoctor@hotmail.com+86 138 8273 9530

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026