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Exploring the Relationship between Bacterial Pneumonia Sepsis and TCM Syndrome Differentiation Based on Peripheral Blood Soluble PD-1/PD-L1

Exploring the Relationship between Bacterial Pneumonia Sepsis and TCM Syndrome Differentiation Based on Peripheral Blood Soluble PD-1/PD-L1

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076552
Enrollment
Unknown
Registered
2023-10-11
Start date
2023-10-01
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Toxin-heat syndrome group:None
Blood stasis syndrome group:None
Acute deficiency syndrome group:None
Fu-organ syndrome group:None

Sponsors

Dongzhimen Hospital of Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Patients must meet the Western medical diagnosis of bacterial pneumonia and sepsis. 2. Patients must meet the TCM diagnosis of poison-heat syndrome, blood stasis syndrome, acute deficiency syndrome, or fu-organ syndrome. 3. Patients must be between 18 and 100 years old, regardless of gender. 4. Patients or their immediate family members must voluntarily participate and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with previous immune system diseases or recent use of immunosuppressants. 2. Patients have severe primary heart disease, liver disease, kidney disease and other organ dysfunction, or have malignant tumors, blood diseases, etc. 3. Pregnant or lactating women. 4. Patients with a history of mental or neurological illness, mental or legal disabilities.

Design outcomes

Primary

MeasureTime frame
Serum soluble programmed cell death receptor 1;Serum soluble programmed cell death-Ligand 1;

Secondary

MeasureTime frame
Serum human monocyte chemoattractant protein 1;Serum angiopoietin-1;Serum angiopoietin-2;

Countries

China

Contacts

Public ContactYan Jun

Dongzhimen Hospital of Beijing University of Chinese Medicine

dzmyyyj@126.com+86 10 8401 3213

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026