Type 2 Diabetes Mellitus
Conditions
Interventions
Group 1-1(T2DM):Three bouts of moderate intensity exercises, including one bout of medium intensity aerobic exercise, one bout of medium intensity anaerobic exercise, and one bout of medium intensity
The sequence of Group B is mixed-anaerobic- aerobic
Group 1-2(Healthy):Three bouts of moderate intensity exercises, including one bout of medium intensity aerobic exercise, one bout of medium intensity anaerobic exercise, and one bout of medium intensi
Group 2-1(T2DM):Three bouts of resistance exercises, including one bout of low intensity resistance exercise, one bout of medium intensity resistance exercise, and one bout of high intensity resistanc
The order of Group B is high-intensity anaerobic exercise - moderate intensity anaerobic exercise - low intensity anaerobic exercise.
Group 2-2(Healthy):Three bouts of resistance exercises, including one bout of low intensity resistance exercise, one bout of medium intensity resistance exercise, and one bout of hi
Sponsors
Department of Public Physical and Art Education, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: The experimental subjects of this study are two populations: healthy adults and T2DM adult patients. The inclusion criteria for healthy adults are: ? fasting blood glucose 3.89-6.1mmol/L, aged between 18-65 years, regardless of gender; ? Normal cognition, able to communicate effectively, able to understand and execute instructions; ? Those who are willing and able to follow the research schedule, procedures, laboratory tests, and other relevant examinations. The inclusion criteria for T2DM patients are: ? Patients diagnosed with T2DM according to World Health Organization standards, aged between 18-65 years, regardless of gender; ? Regularly taking hypoglycemic drugs or using insulin in the past month, regularly eating three meals, stable blood sugar, and no malignant hypoglycemic events in the past week; ? Normal cognition, able to communicate effectively, able to understand and execute instructions; ? Those who are willing and able to follow the research schedule, procedures, laboratory tests, and other relevant examinations. Before the experiment, measure the basic information such as height and weight of all participants, and conduct a treadmill exercise test. All participants agree to voluntarily participate in this experiment and sign an informed consent form.
Exclusion criteria
Exclusion criteria: The exclusion criteria for healthy adults are: ? heavy manual workers; ? Having motor system diseases, and/or contraindications to exercise; ? Eating irregularly; ? Individuals with regular exercise habits in the past year (reaching 150 minutes of moderate to high intensity physical activity per week); ? The researchers believe that the population is not suitable for inclusion in this study. The exclusion criteria for T2DM patients are: ? serious complications, such as coronary atherosclerotic heart disease, hypertensive heart disease, elevated intraocular pressure, value-added diabetes retinopathy, diabetes foot, obvious skin ulceration, diabetes nephropathy, and history of malignant tumors; ? Having motor system diseases, and/or contraindications to exercise; ? Eating irregularly; ? Individuals with regular exercise habits in the past year (reaching 150 minutes of moderate to high intensity physical activity per week); ? The researchers believe that the population is not suitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dynamic glucose;Venous Blood Glucose;Insulin;C peptide;Glycosylated serum protein;Energy expenditure;Oxygen consumption;Carbon dioxide emissions;Respiratory quotient;Daily average glucose;Time in the range;Time below the range;Time above the range;Interleukin-6;Interleukin-8;TNF;Hs-CRP;Prealbumin;Total protein;WBC;RBC;Hemoglobin;Triglyceride;Cholesterol;HDL-cholesterol;LDL-cholesterol; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;Weight;Lean body mass;Body fat;Visceral Fat Area;Resting metabolic rate, RQ, FAT%, CHO%;Daily Steps;Albumin;Globulin;Daily sleep status;Skeletal muscle; | — |
Countries
China
Contacts
Public ContactWen Xu
Department of Public Physical and Art Education, Zhejiang University
Outcome results
None listed