Breast Cancer
Conditions
Interventions
Test group:Deep inspiration breath holding-active breathing control during radiotherapy
Control group:Radiation dose to organs at risk
Sponsors
Sichuan Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Women aged 18-70; (2) New-diagnosed patients with early left-sided breast cancer; (3) Receive standardized breast-conserving surgery and postoperative histopathology of invasive carcinoma with a pathological stage of pT1-2N0M0; (4) At least five titanium clips around the tumor bed, or clear signs of seroma; (5) No history of underlying heart disease (including acute and chronic cardiac insufficiency, coronary heart disease, cardiomyopathy, congenital heart disease, etc.) and normal heart baseline examination results before radiotherapy; (6) The patient meets the requirements of deep inhalation and breath-holding during radiotherapy after standard breathing training: skillfully cooperate with the ABC device to ensure that the breath-holding time is >30s each time, the inspiratory volume is >1L, and the above actions can be repeated 5-6 times. (7) Informed consent.
Exclusion criteria
Exclusion criteria: (1) Pregnant women; (2) The patient has a history of chest radiotherapy; (3) Extensive lesions, and difficulty in achieving negative margins or ideal breast-conserving appearance; (4) Those with no tumor bed area or unclear identification; (5) Inflammatory breast cancer; (6) Cannot tolerate radiation therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of cardiac events within 2 weeks after radiotherapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of cardiac events within 1 year after radiotherapy; | — |
Countries
China
Contacts
Public ContactJun Yin
Sichuan Cancer Hospital
Outcome results
None listed