urinary system /infection
Conditions
Interventions
Gold Standard:The diagnosis of urosepsis typically requires the following two primary criteria:
1.Positive blood culture: This is determined through microbiological examination of a blood sample, wher
Index test:Among the patients who met the inclusion criteria, blood was extracted for analysis of Human myeloid nuclear differentiation antigen (MNDA) after obtaining the informed consent of the patie
Sponsors
The Second Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Men and women between the ages of 18 and 75; 2. Meet any point of a/b below a) Positive blood culture; b) Urine culture positive, blood leukocytes, procalcitonin and other infection indicators increased significantly, and accompanied by obvious symptoms such as fever and chills; 3. Have not participated in other related medical research within the past 6 months; 4. Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Non-urogenic sepsis; 2. Pregnant patients under 18 years old; 3. Complicated with malignant tumor, tuberculosis, blood disease, diabetes and heart disease; 4. Complicated with other serious urological diseases; 5. Infection of other sites is present.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| procalcitonin;Human myeloid nuclear differentiation antigen;c-reactive protein;Plasma leukocyte;blood culture;AUC;sensitiveness;specificity;Optimal cutoff value; | — |
Countries
China
Contacts
Public ContactWenqi Wu
The Second Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed