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Effect of oxycodone on postoperative cognitive function in children

Effect of oxycodone on postoperative cognitive function in children

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076528
Enrollment
Unknown
Registered
2023-10-11
Start date
2023-10-20
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adenoid hypertrophy, tonsil hypertrop

Interventions

group oxycodone preemptive analgesia:Oxycodone (0.2 mg/kg) was given 10 minutes before anesthesia induction and 0.05 mg/kg 10 minutes before operation
group oxycodone postoperative analgesia:Sufentanil (0.3-0.5 ug/kg) was given during anesthesia induction, and oxycodone (0.05 mg/kg) was given 10 minutes before operation
control group:Sufentanil 0.3-0.5 ug/kg was given during anesthesia induction and 0.05 µg/kg was given 10 minutes before operation

Sponsors

Anhui Provincial Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1) age 3-6 years, weight 12-25 kg, ASA grade I-II; 2) no surgical contraindications for tonsillectomy; 3) no allergy to the medication used in this trial; 4) agreed to participate in this study.

Exclusion criteria

Exclusion criteria: 1) abnormal liver and kidney function or complicated with severe pulmonary disease and heart disease; 2) with mental system disease or mental system disease in immediate relatives; 3) with intellectual development defect.

Design outcomes

Primary

MeasureTime frame
Incidence of emergency delirium;detecting serum MCP-1;

Secondary

MeasureTime frame
vital signs;Wake up condition;Adverse reactions;

Countries

China

Contacts

Public ContactXinghui Liu

Anhui Provincial Children's Hospital

xinghuiliu88@163.com+86 152 0560 7634

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026