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Effects of limonene capsules on prevention of postcholecystectomy pain after laparoscopic cholecystectomy: a prospective, single center, three blind, randomized controlled trial

Effects of limonene capsules on prevention of postcholecystectomy pain after laparoscopic cholecystectomy: a prospective, single center, three blind, randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076520
Enrollment
Unknown
Registered
2023-10-11
Start date
2023-10-11
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications after laparoscopic cholecystectomy

Interventions

Oral limonene capsules :Limonene capsules were taken orally on the first day after surgery
Oral placebo:Patients were given an oral placebo on the first day after surgery

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Patients diagnosed as gallstones or gallbladder polyps, with/without acute or chronic cholecystitis, and proposed to be treated by laparoscopic cholecystectomy; 2) Patients within 18 to 75 years old; 3)Patients without previous inflammatory bowel disease.

Exclusion criteria

Exclusion criteria: 1) a long history of chronic abdominal pain (excluding gallbladder disease factors); 2) Patients with intraoperative changes (including laparotomy); 3) Patients who need long-term oral hormones or painkillers; 4) Patients with long-term alcohol addiction or drug addiction; 5) Patients with secondary choledochchal stones after surgery; 6) Patients with suspected postoperative bile duct injury and biliary fistula;

Design outcomes

Primary

MeasureTime frame
Abdominal pain;

Secondary

MeasureTime frame
Diarrhea;Indigestion;

Countries

China

Contacts

Public ContactZhen You

West China Hospital, Sichuan University

youzhen@wchscu.cn+86 138 8226 5200

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026