The correlation between the variability rate of respiratory muscles measured by ultrasound and endotracheal intubation and adverse prognosis in patients with acute hypoxic respiratory failure

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300076510

Enrollment

Unknown

Registered

2023-10-10

Start date

2023-10-31

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute respiratory failure

Interventions

AHRF adult patients treated with HFNC:NA

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: AHRF adult patients (18-90 years old) who were admitted to the ICU of Shanghai General Hospital from October 2022 to April 2026 and were diagnosed with type I respiratory failure

Exclusion criteria

Exclusion criteria: 1. Severe asthma or chronic respiratory failure (including chronic obstructive pulmonary disease or other underlying chronic respiratory diseases); 2. Hemodynamically unstable, SBP 15µg/kg/min or norepinephrine> 15ug/min); 3. GCS score = 12 points; 4. Those who cannot use the HFNC through the nose due to epistaxis, recent nasal surgery or other reasons; 5. Patients who need immediate tracheal intubation (life-threatening hypoxemia PaO2/FiO2< 50mmHg, cardiac or respiratory arrest, etc.) and who refuse to participate in the experiment.

Design outcomes

Primary

Measure	Time frame
HFNC failure rate;	—

Secondary

Measure	Time frame
Respiratory muscle thickness;Variability of respiratory muscle thickness;IC-RDOS;WOB;ROX;	—

Countries

China

Contacts

Public ContactDaonan Chen

Shanghai General Hospital

dnchen1994@163.com+86 176 2122 6779

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026