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A cohort study of the protective effect of daglipzin on acute kidney injury after coronary angiography in patients with diabetes mellitus

A cohort study of the protective effect of daglipzin on acute kidney injury after coronary angiography in patients with diabetes mellitus

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076484
Enrollment
Unknown
Registered
2023-10-10
Start date
2023-10-16
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CI-AKI

Interventions

Study Group (Start taking daglipzin at least 1 week (=7 days) before coronary angiography):None
Control Group (No SGLT-2 inhibitors of any kind were taken 1 week (=7 days) before coronary angiography):None

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1)? coronary angiography, including PCI, CAG and CCTA, has been performed; And the medical records are shown as follows: ?=18 and =100 years old, male or female; ? Patients with CSS combined with T2DM; Start taking daglipzin at least 1 week (= 7 days) before coronary angiography (study group) or have not taken SGLT-2i of any kind in the previous 1 week (= 7 days) (control group); ? Normal liver function or mild injury (alanine aminotransferase = 1.5 times the upper limit of normal); (5) Normal renal function or mild to moderate impairment (glomerular filtration rate = 45 mL/min/1.73m²); 2) Agree to sign informed consent and cooperate with relevant tests, inspections and follow-up.

Exclusion criteria

Exclusion criteria: 1) Suffering from serious diseases, such as malignant tumors, organ failure caused by various reasons, severe immune system diseases, hemodynamic instability, severe infections, etc.; 2) Taking drugs with obvious renal toxicity.

Design outcomes

Primary

MeasureTime frame
CI-AKI events were recorded within 48 hours (KDIGO criteria) after the administration of contrast media;CI-AKI events at 72 h (ESUR criteria) after the administration of contrast media;

Countries

China

Contacts

Public ContactZinan ZHAO

Beijing Hospital

bellazhao2015@163.com+86 151 2007 9895

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026