Atrial fibrillation
Conditions
Interventions
atrial fibrillation with catheter ablation:None
atrial fibrillation without catheter ablation:None
healthy control:None
Sponsors
Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Clinical diagnosis of AF 2) Age 18-80 years 3) Ability to provide written, informed consent
Exclusion criteria
Exclusion criteria: 1) Any previous ablation or surgical therapy for AF 2) Previous organic or degenerative brain diseases (previous stroke, transient ischemic attack, neurodegenerative diseases, encephalitis, head trauma, hydrocephalus, brain tumor, epilepsy, dementia) 3) Intracranial or carotid atrial occlusion or stenosis >50% 4) Depressive state or mental abnormality 5) Current use of sedative, analgesic, anxiolytic, antidepressant or other medication which may affect cognitive function 6) Heavy alcohol consumption over a long period 7) Severe kedney or liver diseases, malignant tumor or any disease that limits life expectancy to less than 1 year 8) Pregnancy or within 30 days after delivery 9) Contraindications for MRI test 10) Colour blindness, or colour perception issues, difficulties in communication or auditory impairment which affect cognitive assessment
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| brain structural changes;cerebral blood flow perfusion;brain functional networks; | — |
Primary
| Measure | Time frame |
|---|---|
| cognitive function; | — |
Countries
China
Contacts
Public ContactZhao Xingquan
Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed