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Multiparametric MRI and MR elastography for the assessment of chronic allograft injury and its progression after kidney transplantation

Multiparametric MRI and MR elastography for the assessment of chronic allograft injury and its progression after kidney transplantation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076466
Enrollment
Unknown
Registered
2023-10-09
Start date
2022-02-01
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney transplantation

Interventions

Gold Standard:Pathology of biopsy
Index test:Multiparametric MRI and MR elastography

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Follow-up patients =1 year after kidney transplantation (2) Age=18 years old (3) planed to conduct kidney transplant biopsy.

Exclusion criteria

Exclusion criteria: (1) Patient with contraindication of MRI examination (Metal implants in the body) (2) Patients with abdominal hernia or postoperative abdominal hernia; (3) Presence of other abdominal injuries; (4) Patients with poor basic condition and difficulty in holding their breath (severe cardiopulmonary disease)

Design outcomes

Primary

MeasureTime frame
Interstitial fibrosis;Stiffness;Renal blood flow;Apparent diffusion coefficient;T1 mapping;Renal volume;Accuracy;Sensitivity;Specificity;Hazard ratio;Allograft dysfunction;—

Secondary

MeasureTime frame
Tubular atrophy;Inflammation score;Estimated glomerular filtration rate (eGFR);Allograft loss;—

Countries

China

Contacts

Public ContactSong Bin

West China Hospital, Sichuan University

cjr.songbin@vip.163.com+86 189 8060 1592

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026