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Association of plasma markers with postoperative delirium in elderly patients undergoing cardiac surgery: an observational nested cohort study

Association of plasma markers with postoperative delirium in elderly patients undergoing cardiac surgery: an observational nested cohort study

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076456
Enrollment
Unknown
Registered
2023-10-09
Start date
2023-10-10
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium

Interventions

Trial group:None

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age 60-80 years old; (2) ASA grade ?-?; (3) Duration of education =6 years; (4) Patients receiving coronary artery bypass surgery under elective general anesthesia; (5) Agree and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) Montreal Cognitive Assessment Scale (MoCA-B) < 22 points; (2) pre-existing psychological and/or psychiatric illness; (3) have a clear history of stroke; (4) Parkinson's disease, epilepsy history; (5) Brain tumor or previous history of craniocerebral surgery; (6) severe hepatic or renal insufficiency; (7) Impairment of hearing, vision or speech that prevents communication.

Design outcomes

Primary

MeasureTime frame
NFL;Tau;inflammatory factor;The incidence, duration, and severity of POD;

Countries

China

Contacts

Public ContactLichao Di

The Second Hospital of Hebei Medical University

dilichao@163.com+86 311 6600 3887

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026