blepharitis
Conditions
Interventions
experimental group:micro blepharo exfoliation+terpinen-4-ol lid wipes
control group:terpinen-4-ol lid wipes
Sponsors
Hankou Aier Eye Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Meet the diagnostic criteria of demodex blepharitis: 1. Chronic or subacute course of binocular disease, with eye symptoms such as red eyes, itching eyes, foreign body sensation, or accompanied by recurrent attacks and refractory chalazion. 2. Abnormal eyelashes, lipid-cuff secretions at the root of eyelashes (with diagnostic value), can be accompanied by blepharon congestion and hypertrophy. 3. Demodex was tested positive. Recommended criteria for positive Demodex follicularis test: (1) Demodex counts in all stages; (2) In adult patients, demodex counts reached 3 /3 eyelashes in any one of the 4 eyelids; (3) If it is less than the above criteria, it is suspected to be positive, which should be combined with clinical manifestations. If necessary, other pathogenic microorganisms, such as bacteria and fungi, can be examined at the same time. If the above three criteria are met at the same time, the diagnosis of demodex blepharitis can be confirmed. If demodex mites are detected in eyelashes but the count is not up to the standard, the samples can be taken repeatedly and the in vivo confocal laser microscope can be used for auxiliary examination. If the count is still not up to the standard, it can be diagnosed as suspected demodex blepharitis. Demodex blepharitis is not diagnosed only in patients with positive demodex without clinical symptoms and signs
Exclusion criteria
Exclusion criteria: (1) Patients with systemic immune diseases; (2) recent history of acute eye infection, (3) patients who cannot understand or cooperate with treatment, (4) patients with systemic severe disease intolerance to treatment; (5) Pregnancy and breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Demodex load ;Palpebral sign; | — |
Secondary
| Measure | Time frame |
|---|---|
| Eye surface symptom score;Eye surface signs; | — |
Countries
China
Contacts
Public ContactZeng Qingyan
Hankou Aier Eye Hospital
Outcome results
None listed