Perioperative stress response
Conditions
Interventions
Propofol group (P group):Anesthesia induction using propofol 1.5-2.5mg/kg, sufentanil 0.2-0.5ug/kg, and rocuronium 0.6mg/kg
Ciprofol group (C group) :Anesthesia induction using ciprofol 0.4mg/kg, sufentanil 0.2-0.5ug/kg, and rocuronium 0.6mg/kg
Sponsors
Gansu provincial hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age = 18 and = 60 years old Body mass index (BMI) = 18 and = 30kg/m2 ASA is classified as Grade I-II Patients who voluntarily participate in this trial and sign an informed consent form.
Exclusion criteria
Exclusion criteria: Patients with asthma, hypertension, diabetes and coronary heart disease in the past Patients with severe liver and kidney dysfunction Patients who have been taking hormone drugs for a long time Patients who temporarily change their anesthesia methods due to various reasons Patients with difficulty in tracheal intubation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Heart rate;Plasma cortisol;Plasma epinephrine;Plasma norepinephrine; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of hypotension;The incidence of bradycardia;The incidence of body moving;The incidence of choking cough;The incidence of tearing;Change amplitude of Ai value;Use of remedial anesthetics;Usage of vasoactive drugs; | — |
Countries
China
Contacts
Public ContactReng dongqing
Gansu provincial hospital
Outcome results
None listed