post-stroke fatigue
Conditions
Interventions
treatment group:Repetitive transcranial stimulation therapy
control group:Shame stimulation therapy
Sponsors
The First Affiliated hospital of USTC
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Age = 18 years 2) Clinical criteria: (1) First stroke episode within 90d ± 30d (2) FSS scale score =36 within 2 weeks of stroke onset (3) FSS scale score = 36 before rTMS treatment (4) Signed informed consent form
Exclusion criteria
Exclusion criteria: 1) Infarct lesions accumulate in the cerebral cortex 2) mRS > 2 points 3) recurrent cerebrovascular events during the screening period 4) Use of centrally acting drugs that may affect fatigue, depression and anxiety levels during the screening period, such as reserpine, fluoxetine, paroxetine, sertraline, citalopram, fluvoxamine benzodiazepines, hormones, etc. 5) Change in NIHSS score score <0 (indicating neurological deterioration) from the start of the screening period to the end of the screening period 6) Severe dementia or impaired consciousness, unable to complete scale related tests 7) Concomitant stroke with other neurological related disorders or psychiatric related severe disorders (including schizophrenia, severe cognitive impairment, multiple sclerosis, Parkinson's syndrome, traumatic brain injury, epilepsy, cerebral oedema, etc.) 8) Patients with cumulative pre- and post-stroke circulation 9) Pregnant and lactating women 10) Claustrophobia 11)Metallic foreign bodies such as pacemakers in the body
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fatigue severity scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Apathy Evaluation Scale;Hamilton Anxiety Scale;Hamilton Depression Scale;Montreal Cognitive Assessment;Health-Related Quality of Life;National Institute of Health stroke scale;Modified Rankin Scale; | — |
Countries
China
Contacts
Public ContactWen Sun
Cerebrovascular Disease Center / Department of Neurology, the First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed