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Real-World Evidence of Long-Term Survival Benefits of the Perioperative FLOT Regimen in Patients with locally advanced Gastric Cancer

Real-World Evidence of Long-Term Survival Benefits of the Perioperative FLOT Regimen in Patients with locally advanced Gastric Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076411
Enrollment
Unknown
Registered
2023-10-08
Start date
2023-10-10
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric cancer

Interventions

FLOT-first (patients in the FLOT group received one to three cycles of FLOT regimen chemotherapy prior to surgery):None
Surgery-first (Surgical treatment was performed directly after diagnosis.):None

Sponsors

Lanzhou University Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria required patients to meet the T3-4 stage, histologically confirmed adenocarcinoma, undergone curative surgery, absence of distant metastasis, age below 75 years, and ECOG performance status score no more than 2.

Exclusion criteria

Exclusion criteria: Exclusion criteria included a history of previous malignancies, residual gastric cancer, and prior preoperative radiation therapy.

Design outcomes

Primary

MeasureTime frame
Overall survival;—

Secondary

MeasureTime frame
Tumor response;—

Countries

China

Contacts

Public ContactZuoyi Jiao

Lanzhou University Second Hospital

jiaozy@lzu.edu.cn+86 138 9341 5219

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026