Pain after thoracic surgery
Conditions
Interventions
General group:Sufentanil 0.5 µg/kg was given for anesthesia induction, and remifentanil 0.25 µg/kg/min was given for anesthesia maintenance
Alfentanil group:Alfentanil 50 µg/kg was given for anesthesia induction and 1 µg/kg/min for anesthesia maintenance
Sponsors
Second Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Surgical patients who undergo thoracoscopic radical resection of lung cancer under general anesthesia; (2) Age: Age< 65 years old; (3) Gender is not limited; (4) Clear consciousness, no cognitive and language expression disorders; (5) no mental and neurological disorders; (6) ASAI ~ II patients; (7) The patient agrees to participate in this experiment and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Have participated in other clinical trials within 4 weeks before the start of this study; (2) Have used opioids within 24 hours; (3) Severe heart, liver, lung, or kidney insufficiency (that is, the index is more than 1 times higher than normal);(4) Have a history of respiratory diseases; (5) Severe cognitive dysfunction; (6) Complete aphasia or deaf and dumb (7) Suspected difficulty in intubation (Mallampati grade 3~4, mouth opening less than 3.5cm) ;(8) tolerance and allergy to alfentanil, or have been discontinued due to adverse reactions during use; (9) drug and/or alcohol abuse; (10) There were underlying symptoms related to analgesic drugs before enrollment, and (11) Patients were reluctant to join this experiment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic indicators; | — |
Countries
China
Contacts
Public ContactYang Dong Lin
The Second Xiangya Hospital of Central South University
Outcome results
None listed