Skip to content

Analysis of red blood cell injury in community-acquired pneumonia complicated with sepsis based on multi-omics

Analysis of red blood cell injury in community-acquired pneumonia complicated with sepsis based on multi-omics

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076395
Enrollment
Unknown
Registered
2023-10-07
Start date
2023-10-07
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Community-acquired pneumonia complicated with sepsis

Interventions

CAP -sepsis :none

Sponsors

Fourth Medical Center of the Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1 ) Critically ill patients admitted to the ICU of our hospital from October 1,2023 ; And 2 ) Conform to the diagnostic criteria of sepsis 3.0 ; And 3 ) Age = 18 years ; And 4 ) Patients with community-acquired pneumonia infected by drug-resistant bacteria ; And 5 ) Patients met the diagnostic criteria for sepsis and community-acquired pneumonia developed by the American Society of Critical Care Medicine ; And 6 ) CAP-sepsis group was defined according to the infection indications of patients with community-acquired pneumonia complicated with sepsis and the SOFA score of severe patients ( sepsis patients with SOFA score = 2 ).

Exclusion criteria

Exclusion criteria: 1 ) age < 18 years ; 2 ) pregnant and lactating women ; 3 ) Patients with hematological diseases such as sickle cell anemia ; 4 ) Long-term use of immunosuppressants and glucocorticoids ; 5 ) Hemoglobinopathy ; 6 ) HIV positive patients ; 7 ) Incomplete case information ; 8 ) Any other disease or treatment that may affect red blood cell metabolism (chronic kidney disease, heart valve prosthesis, chemotherapy, taking anticoagulants, etc. ).

Design outcomes

Primary

MeasureTime frame
Red blood cell;

Countries

China

Contacts

Public ContactKai Dai

Fourth Medical Center of the Chinese PLA General Hospital

chenlzu2005@163.com+86 185 0031 1466

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026