vulvovaginal candidiasis
Conditions
Interventions
oral Azmasol , 2 pills twice a day for 6 days
Treatment group 2:Oral fluconazole 150mg, once a day for 1 day
Treatment group 1:Oral fluconazole 150mg once a day for 1 day and vaginal miconazole 400mg once a night for 3 days
vaginal miconazole 400mg, once a night for 3 days
if symptoms are effectively controlled after 7 days from the first treatment, continue oral Azmasol 1 pill daily for 12 weeks for consolidation.
Treatment group 3:Vaginal miconazole suppositories 400mg once a night for 3 days and oral Azmasol, 2 sticks twice a day for 6 days
Sponsors
Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Healthy women who are sexually active; 2. 18 years of age or older; 3. Have not consumed cranberry juice, polyphenols or antioxidant supplements within the past 2 weeks; 4. = 2 recurrent episodes of vulvovaginal candidiasis in the past 6 months; or 5. = 3 episodes of recurrent vulvovaginal candidiasis in the past 12 months.
Exclusion criteria
Exclusion criteria: 1. Have used antibiotics or cranberry extract within the last two weeks; 2. Have a history of antibiotic allergy; 3. Have a history of cranberry allergy; 4. Are pregnant or in the process of preparing for pregnancy; 5. Patients with kidney stones; 6. With a history of kidney transplantation; 7. Patients with renal tumours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical cure rate;Compound cure rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical improvement;Microbial clearance; | — |
Countries
China
Contacts
Public ContactDongmei Wei
West China Second Hospital,Sichuan University
Outcome results
None listed