Strabismus
Conditions
Interventions
Placebo group:Patients were premedicated with an equal volume of 0.9% saline.
Esketamine 0.5 mg/kg group:Patients were premedicated with intranasal esketamine 0.5 mg/kg.
Esketamine 1 mg/kg group:Patients were premedicated with intranasal esketamine 1 mg/kg.
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 5 Years
Inclusion criteria
Inclusion criteria: 1. ASA physical status I or II; 2. Aged 2-5 years; 3. Scheduled for elective strabismus surgery.
Exclusion criteria
Exclusion criteria: 1. Potentially difficult airway; 2. Asthma; 3. Any sign of upper respiratory infection; 4. Intake of sedative or analgesic medication within 48 hours before surgery; 5. Psychosis; 6. Body mass index > 30 kg/m2; 7. Allergy to study drugs; 8. Major life changes 1 month before the operation, such as the divorce of parents, death of parents, moving to a new home, changing to a new kindergarten, etc.; 9. Any other conditions that precluded study inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The minimum alveolar concentration for laryngeal mask airway insetion of sevoflurane; | — |
Secondary
| Measure | Time frame |
|---|---|
| Induction quality;Incidence of emergence delirium;Incidence of postoperative negative behavior changes;Length of postanesthesia care unit stay;Emergence time;Parental satisfaction;Peak emergence delirium score; | — |
Countries
China
Contacts
Public ContactYao Yusheng
Fujian Provincial Hospital
Outcome results
None listed