Methamphetamine addiction combined with HIV infection and poor immune reconstitution
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age range from 18 to 65 years old, regardless of gender; 2.Previously used methamphetamine drugs and met the diagnostic criteria for amphetamine withdrawal; 3.HIV patients should receive standard ART treatment for at least 1 year; 4.Meets the diagnostic criteria for poor immune reconstitution; 5. After treatment, the viral load was controlled at<50 Copies · m L-1 for more than 1 year; 6.The patient voluntarily signs an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Serious opportunistic infections are not controlled; 2. Merge with other serious organic diseases (such as tumors, cardiovascular diseases, liver cirrhosis) or mental disorders (such as schizophrenia); 3.Participate in other clinical trials within 3 months; 4.Received other treatment methods other than ART regimen within 1 month; 5.Combined liver and kidney dysfunction; Those who meet the inclusion criteria but meet one of the above conditions will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD4+T cell count; | — |
Secondary
| Measure | Time frame |
|---|---|
| Immune reconstruction efficiency;T cell subpopulation;T cell activation level and function;T cell proliferation and apoptosis;Opportunistic infection;; | — |
Countries
China
Contacts
Chengdu University of Traditional Chinese Medicine