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Acupuncture improves the survival and function of T cells in methamphetamine addicts with HIV infection and immune non-responders

Acupuncture improves the survival and function of T cells in methamphetamine addicts with HIV infection and immune non-responders

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076363
Enrollment
Unknown
Registered
2023-10-07
Start date
2023-10-09
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Methamphetamine addiction combined with HIV infection and poor immune reconstitution

Interventions

Experimental group:TEAS+ART treatment
control group:sham-TEAS+ART treatment

Sponsors

Chengdu University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Age range from 18 to 65 years old, regardless of gender; 2.Previously used methamphetamine drugs and met the diagnostic criteria for amphetamine withdrawal; 3.HIV patients should receive standard ART treatment for at least 1 year; 4.Meets the diagnostic criteria for poor immune reconstitution; 5. After treatment, the viral load was controlled at<50 Copies · m L-1 for more than 1 year; 6.The patient voluntarily signs an informed consent form.

Exclusion criteria

Exclusion criteria: 1.Serious opportunistic infections are not controlled; 2. Merge with other serious organic diseases (such as tumors, cardiovascular diseases, liver cirrhosis) or mental disorders (such as schizophrenia); 3.Participate in other clinical trials within 3 months; 4.Received other treatment methods other than ART regimen within 1 month; 5.Combined liver and kidney dysfunction; Those who meet the inclusion criteria but meet one of the above conditions will be excluded.

Design outcomes

Primary

MeasureTime frame
CD4+T cell count;

Secondary

MeasureTime frame
Immune reconstruction efficiency;T cell subpopulation;T cell activation level and function;T cell proliferation and apoptosis;Opportunistic infection;;

Countries

China

Contacts

Public ContactRen yu lan

Chengdu University of Traditional Chinese Medicine

Renxg2468@163.com+86 136 8909 8226

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026