Anesthetic effect and brain protection of cyclopofol in patients undergoing brain tumor surgery

Anesthetic effect and brain protection of cyclopofol in patients undergoing brain tumor surgery - Brain protective effect of cyclopofol on patients with brain tumor

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300076348

Enrollment

Unknown

Registered

2023-10-06

Start date

2023-10-06

Completion date

Unknown

Last updated

2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral tumor

Interventions

experimental group:The observation group was injected with cyclopofol (0.5-2 mg/kg/h)

control group:The control group was injected with propofol (2-5 mg/kg/h)

Eligibility

Sex/Gender

All

Age

16 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Patients diagnosed with brain tumor by CT and MRI and treated with surgery; 2) ASA Grade I-III; 3) BMI 18-30 m2;

Exclusion criteria

Exclusion criteria: 1) Combined with serious dysfunction of vital organs; 2) Dementia patients; 3) History of drug allergy and mental cognitive impairment; 4) Patients with metastatic malignant tumors.

Design outcomes

Primary

Measure	Time frame
S100 beta protein level;	—

Secondary

Measure	Time frame
hemodynamics;	—

Countries

China

Contacts

Public ContactTanchengwei

Jinyang Hospital Affiliated to Guizhou Medical University, Guiyang Second People's Hospital

18198632008@163.com+86 181 9863 2008

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026