Lung disease
Conditions
Interventions
experimental group:The experimental group was given oxycodone hydrochloride injection of 0.1mg/kg, diluted with 0.9% sodium chloride injection to a concentration of 1mg/h, and intravenous injection wa
control group:Administer 50mg of flurbiprofen axetil at the same time point
Sponsors
Dongguan People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Perform thoracoscopic surgery with preserved autonomous breathing, including lung segment resection under preserved autonomous breathing thoracoscopy, mediastinal mass resection under preserved autonomous breathing thoracoscopy, and radical lung cancer resection under preserved autonomous breathing thoracoscopy, sign an "informed consent form" and indicate the date;2. Age range from 18 to 65 years old;3. Patient body mass index BMI 18-27 kg/m2;4. The American Society of Anesthesiologists (ASA) is rated as either I or II;5. No major heart, brain, lung, kidney or other diseases
Exclusion criteria
Exclusion criteria: 1. Drug abuse, including but not limited to opioids, amphetamines, methamphetamine, ketamine, etc; 2. Allergies to opioids and contraindications related to investigational drugs: Allergies to oxycodone, non-steroidal anti-inflammatory drugs, or any other components of the drug, chronic obstructive airway disease, pulmonary heart disease, chronic bronchial asthma, and severe hypertension patients; 3. Neurological diseases such as peripheral neuropathy and mental illness; 4. Other situations that the researchers believe are not suitable for participation in this study, such as deafness, Parkinson's disease, communication disorders, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting NRS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sufentanil and refentanil consumption;The number of times the patient controls the addition of the intravenous analgesia pump;Additional amounts of analgesic medication;Postoperative adverse effects; | — |
Countries
China
Contacts
Public ContactWeiming Liang
Dongguan People's Hospital
Outcome results
None listed