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A prospective, single center, randomized, controlled study comparing conventional magnifying endoscopy mode with white light endoscopy mode for opportunistic screening of upper gastrointestinal early cancer and precancerous lesions

A prospective, single center, randomized, controlled study comparing conventional magnifying endoscopy mode with white light endoscopy mode for opportunistic screening of upper gastrointestinal early cancer and precancerous lesions

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076327
Enrollment
Unknown
Registered
2023-10-03
Start date
2023-10-17
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early cancer and precancerous lesions of the upper gastrointestinal tract

Interventions

White light endoscopy group:Blank control group
Conventional magnifying endoscopy group:Conditional control group

Sponsors

Shandong Second Provincial General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: All patients aged = 18 who will go painless gastroduodenoscopy at our hospital's endoscopy center and have agreed to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Patients with advanced tumors in the throat; 2. Previous history of surgical removal of upper gastrointestinal organs; 3. Currently using antithrombotic drugs; 4. Confirmed or suspected upper gastrointestinal cancer in other hospitals; 5. Pregnant and lactating female patients; 6. Severe infection or potential illness; 7. Severe dysfunction of vital organs (such as heart, lung, liver, kidney, brain, or hematopoietic function); 8. Participated in this study or similar studies within the past 6 months; 9. Conduct emergency endoscopic examination; 10. Patients who are unwilling to participate in this study, refuse to sign informed consent forms, or have poor compliance based on comprehensive judgment.

Design outcomes

Primary

MeasureTime frame
Detection rate of early cancer and precancerous lesions in the upper gastrointestinal tract;Positive predictive values for early cancer and precancerous lesions in the upper gastrointestinal tract;Negative predictive values for early cancer and precancerous lesions in the upper gastrointestinal tract;

Secondary

MeasureTime frame
Biopsy site;Number of biopsies;Bleeding after biopsy;Perforation after biopsy;operation time;

Countries

China

Contacts

Public ContactZhi Wei

Shandong Second Provincial General Hospital

bj-1256@163.com+86 139 6915 6983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026