Severe fever with thrombocytopenia syndrome
Conditions
Interventions
Intervention:Symptomatic treatment+Tocilizumab
Sponsors
The Eighth Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients diagnosed with SFTS through laboratory testing
Exclusion criteria
Exclusion criteria: ? Age<18 years old; ? The patient has received systematic antiviral therapy or immunotherapy within 6 months. ? Patients have severe progressive chronic diseases or tumors, such as severe heart failure, severe liver and kidney failure, and other important organ failure, as well as hematological tumor diseases or uncontrolled solid tumors; ? Patients with poor immune function or active tuberculosis infection; ? Patients who are allergic to Tocilizumab; ? PLT < 20 × 10^9/L; ? Pregnant and lactating women; ? Subject is unwilling or unable to follow protocol procedures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Case fatality rate of SFTS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Days required for PLT and WBC to return to normal levels;Time to resolution of main clinical symptoms and viral load;Time for blood biochemical indicators to return to normal levels;IL-6 serum level;adverse event; | — |
Countries
China
Contacts
Public ContactBao Pengtao
The Eighth Medical Center of Chinese PLA General Hospital
Outcome results
None listed