Early diagnosis and treatment of late life dementia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300076307

Enrollment

Unknown

Registered

2023-09-30

Start date

2023-10-01

Completion date

Unknown

Last updated

2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementia

Interventions

Gold Standard:Presence of mild impairment in one more or cognitive domains (e.g., attention, executive function, language, memory, perceptual-motor abilities, social cognition) relative to expectation

Index test:EEG, functional NIR, neuropsychological scales, MRI, blood

Eligibility

Sex/Gender

All

Age

50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Any gender, age 50-80 years old; diagnosed by two or more associate physicians alone with ICD-10 diagnostic criteria; MMSE score below 25 and MoCA score below 26 for dementia.

Exclusion criteria

Exclusion criteria: Those with severe physical illnesses, such as severe heart disease, malignant tumors, etc.; those with severe mental illnesses; those with severe depression; those with allergies to the components of the drugs and contrast media used in this study; those with ophthalmic diseases or those who have undergone eye surgeries; and those who do not sign the informed consent form.

Design outcomes

Primary

Measure	Time frame
electroencephalogram, EEG;Near-infrared brain function, fNIRS;MRI;Accuracy ;Sensitivity ;Specificity ;	—

Secondary

Measure	Time frame
Positive predicative value, PPV;	—

Countries

China

Contacts

Public ContactXi Mei

Ningbo Kangning Hospital

meixi18401856@163.com+86 574 2630 2520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026