Depressive disorder
Conditions
Interventions
Paroxetine group:NA
Fluoxetine group:NA
Sertraline group:NA
Citalopram group:NA
Fluvoxamine group:NA
Venlafaxine group:NA
Duloxetine group:NA
Fluoxetine group:NA
Sponsors
Department of Pharmacy, ZhongDa Hospital, Southeast University
Eligibility
Sex/Gender
All
Age
10 Years to 99 Years
Inclusion criteria
Inclusion criteria: ? Meets the DSM-V or ICD-10 diagnostic criteria for depression; ? The patient takes medication according to medical advice during hospitalization; ? The interval between two laboratory biochemical tests after admission is (15 ± 5) days ? No age limit, no gender limit
Exclusion criteria
Exclusion criteria: ? Simultaneously using two or more antidepressants of the same type; ? Use of hypoglycemic drugs, lipid-lowering drugs and other drugs that have an impact on biochemical indicators ? Patients with diabetes, hyperlipidemia and serious physical diseases with abnormal results of the first laboratory biochemical test; ? Pregnant or lactating women; ? Individuals with a history of drug allergies; ? For patients with first-time medication, discontinuation, and change of medication during hospitalization, the first laboratory test is = 1 day earlier than the start of medication, and the last test is = 1 day later than the discontinuation and change of medication; ? Patients who do not meet the inclusion criteria, do not use medication according to regulations, and have incomplete information
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction rate of Hamilton Depression Scale-17 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety Scale; | — |
Countries
China
Contacts
Public ContactZhong Lingjun
ZhongDa Hospital, Southeast Universtiy
Outcome results
None listed