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Study on the response mechanism of fNIRS based on the pathogenesis of "Shi Yu Yang E" acupuncture in the treatment of mild to moderate depressive disorder

Clinical study on the treatment of depressive disorder based on "brain-gut interaction" acupuncture based on dampness theory

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076292
Enrollment
Unknown
Registered
2023-09-28
Start date
2023-09-29
Completion date
Unknown
Last updated
2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depressive disorder

Interventions

Treatment group:Acupuncture at CV12, CV4, PC6, ST36, SP6.
Control group:Select the acupuncture points in the treatment group perpendicular to the direction of the meridians, and acupuncture at a 0.5-1cm side opening.

Sponsors

Affiliated Hospital of Chengdu University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The following criteria must be met at the same time to be included: (1) Meet the diagnostic criteria for depressive disorder in the "Diagnostic and Statistical Manual of Mental Disorders" (fifth edition) and the "Diagnostic and Efficacy Standards for Traditional Chinese Medicine Diseases and Syndromes - Depression" (ZY/T001.1-94); (2) Aged 18 to 65 years old, no gender limit; (3) 53 points = SDS score = 72 points, and SAS score = 69 points; (4) Have not received acupuncture treatment in the past month; (5) Those who sign the informed consent form and voluntarily participate in this study.

Exclusion criteria

Exclusion criteria: If any of the following applies, it must be excluded: (1) Alcohol or drug abusers; (2) Pregnant or lactating women; (3) Those with serious primary diseases such as cardiovascular, lung, liver, kidney and hematopoietic system; (4) People with organic mental disorders, emotional disorders caused by psychoactive substances and non-addictive substances have serious impairment of social functions; (5) Anyone with severe skin infection at acupoints, or other serious wasting diseases such as progressive malignant tumors, who are prone to infection and bleeding.

Design outcomes

Primary

MeasureTime frame
SDS;

Secondary

MeasureTime frame
SAS;SF-36;TCM syndrome score table;Symptom elimination rate;fNIRS;

Countries

China

Contacts

Public ContactMiao Runqing

Affiliated Hospital of Chengdu University of Traditional Chinese Medicine

52402290@qq.com+86 175 0280 8126

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026