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Safety and feasibility of bronchoscopic holmium laser continuous cryoablation for the treatment of airway stenosis caused by tissue hyperplasia after tracheal intubation

Safety and feasibility of bronchoscopic holmium laser continuous cryoablation for the treatment of airway stenosis caused by tissue hyperplasia after tracheal intubation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076289
Enrollment
Unknown
Registered
2023-09-28
Start date
2023-10-06
Completion date
Unknown
Last updated
2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

airway stenosis caused by tissue hyperplasia after tracheal intubation

Interventions

Group of bronchoscopic holmium laser sequential cryoablation:None

Sponsors

Xiamen Humanity Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Airway stenosis occurs after oral/nasal tracheal intubation or tracheotomy intubation; 2. Hyperplastic tissues such as granulation tissue hyperplasia and fibroplasia grow into the trachea lumen, resulting in airway stenosis; 3. Continued holmium laser cryoablation under bronchoscope was performed.

Exclusion criteria

Exclusion criteria: 1. Airway stenosis mainly caused by tracheal softening, collapse, scar contraction, etc., with no hyperplasia in the tracheal lumum; 2. The endotracheal intubation cannot be removed after ablation, and the endotracheal intubation still needs to be retained for a long time, which affects the observation of ablation efficacy; 3. After ablation, the patient refused bronchoscopy or CT examination for various reasons, or lost follow-up.

Design outcomes

Primary

MeasureTime frame
Ablation frequency;Ablation effect;

Secondary

MeasureTime frame
Degree of airway stenosis;Operation time;

Countries

China

Contacts

Public ContactQingjie Yang

Xiamen Humanity Hospital

yqj00001@163.com+86 159 6023 2897

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026