Pain after thoracic surgery
Conditions
Interventions
RPB:Subjects underwent deep frontal serratus plane block with 0.375% ropivacaine in combination with an opioid analgesic pump for postoperative analgesia
LBB:Participants used 0.665% bupivacaine liposomes for deep serratus plane block for postoperative analgesia
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) the patients who intend to undergo thoracoscopic lobectomy are the same group of doctors. 2) male or female, aged 18-65 3) male weight = 50, female weight = 45, BMI19.0~26.0kg/m2 4) ASA rating of anesthesia is grade ? ~ ?. 5) before the test, have a detailed understanding of the nature, significance, possible benefits, possible inconvenience and potential danger, understand the research procedure and sign the informed consent form voluntarily in writing.
Exclusion criteria
Exclusion criteria: 1) the patient refused to perform anterior serratus plane block. 2) the patient has specific allergic diseases (asthma, urticaria, eczema, etc.) or is known to be allergic to bupivacaine 3) the area of the anterior chest wall of the patient is damaged or infected. 4) the coagulation function of the patient was abnormal, APTT > 33.8S or PT > 12.1s before operation. 5) the patient has a history of chronic neuropathic pain. 6) patients participate in other clinical trials at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of recovery;Time to first use of analgesics;Extubation time;Serum concentrations of TNF-a, IL-1ß and IL-6 were measured.;ICU dwell time;Time to first exhaust bowel movements;Incidence of postoperative pruritus;the first time of out of bed;Postoperative opioid analgesic use;Incidence of postoperative nausea and vomiting;Length of hospital stay;hospitalization expenses;Quality of sleep after surgery;Perioperative satisfaction;Adverse event rate; | — |
Countries
China
Contacts
Public ContactChen Shibiao
The First Affiliated Hospital of Nanchang University
Outcome results
None listed