Anesthesiology
Conditions
Interventions
Group R1:Remimazolam besylate 0.2mg/kg combined with Alfentanyl 5ug/kg
Group P:Propofol 2mg/kg combined with Alfentanyl 5ug/kg
Group R2:Remimazolam besylate 0.3mg/kg combined with Alfentanyl 5ug/kg
Group R3:Remimazolam besylate 0.4mg/kg combined with Alfentanyl 5ug/kg
Sponsors
Hospital of Reproductive Medicine Affiliated to Shandong University
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: ?20=age =45 years; ?18.5 kg/m2 < body mass index (BMI) < 27.9 kg/m; ?American Society of Anesthesiologists [ASA] classification I or II ; ?Patients undergoing ultrasound-guided transvaginal egg retrieval; ?Patients clear understanding and voluntary participation in the study and signed informed consent form.
Exclusion criteria
Exclusion criteria: ?Patients with contraindications to deep sedation/general anesthesia or a history of sedation/anesthesia accidents; ?Allergy or contraindication to benzodiazepines, opioids, propofol, lidocaine, and other drugs and their components; ?Modified Mallampati Score with grade III and above; ?The number of dominant follicles was > 20 or < 3; ?History of mental disorder or psychological disorder, recent use of antipsychotic drugs or antidepressant drugs; ?History of PONV; ?Long-term use of sleeping pills or sedative drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of sedation; | — |
Secondary
| Measure | Time frame |
|---|---|
| General information of patients;Hemodynamics index;Time from the start of drug administration to the first MOAA/S score < 2;Recovery time;Time to fully allert;The number and grade of intraoperative body movements;Intraoperative drug dosage;Adverse reaction;Time of Operation ; | — |
Countries
China
Contacts
Public ContactXin Zhang
Hospital of Reproductive Medicine Affiliated to Shandong University
Outcome results
None listed