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Clinical features, treatment, and outcomes of aspiration pneumonia patients with low eosinophil counts:a prospective cohort study

Clinical features, treatment, and outcomes of aspiration pneumonia patients with low eosinophil counts

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300076254
Enrollment
Unknown
Registered
2023-09-28
Start date
2016-01-01
Completion date
Unknown
Last updated
2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aspiration pneumonia

Interventions

Eosinopenia Group:None
Non-eosinopenia Group:None

Sponsors

Shanxi Bethune Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: (1) an aspiration event witnessed by an around person, such as family members, caregivers, and medical staff or factors indicating an aspiration event; (2) acute respiratory symptoms and the presence of respiratory system findings suggestive of pneumonia, such as cough, sputum, fever, tachypnea and pathological respiratory sounds; and (3) compatible radiologic findings of aspiration pneumonia on chest CT.

Exclusion criteria

Exclusion criteria: (1) infiltrative lung lesion in dependent position without bacterial infection signs; (2) confirmation of different diagnosis (eg, lung cancer, tuberculosis, asthma, COPD, bronchiectasis, COVID-19); and (3) patients with a history of solid tumors or hematological malignancy, autoimmune and endocrine disorders, parasitic and fungal diseases, allergic disorders and patients received steroids within the previous six months patients, and suffering from disease or receiving therapy that suppresses the bone marrow activity. All these clinical conditions can affect peripheral eosinophil counts.

Design outcomes

Primary

MeasureTime frame
Eosinophil;CURB-65 Score;30-day fatality rate;

Secondary

MeasureTime frame
Duration of pneumonia treatment (days);Number of antibiotic changes (times);Supplemental nutrient intake (kcal);Length of stay (days);The total length of stay (days);Number of infections during the study period;

Countries

China

Contacts

Public ContactXia Jing

Shanxi Bethune Hospital

13293811693@163.com+86 132 9381 1693

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 18, 2026