Tubacco Use Disorder
Conditions
Interventions
Group group location rTMS stimulation group.:rTMS treatment was performed at the location of the left DLPFC, which is the most commonly used location for addiction studies such as smoking and drugs
Individualized location rTMS stimulus:According to the Cue-Craving task, the subjects' performance in the face of two conditions of smoking stimulus and neutral stimulus (smoking stimulus -- neutral s
Individualized location:In the resting state data, NAcc (Nucleus Accumbens) is taken as ROI, and the cortex located in the frontal lobe with which it is associated is selected as the target of rTMS.
Sham Group:rTMS sham treatment, that is, to make subjects feel that they are undergoing rTMS treatment, but they are not actually undergoing RTMS treatment.
Craving evoked -rTMS stimulation group:The subjects in this group received the same rTMS stimulus as the first group. The difference was that five minutes before rTMS stimulation, subjects were presen
Sponsors
Hangzhou Normal University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria for Tubacco Use Disorder were smokers who had smoked 10 or more cigarettes per day in the past year, and non-smokers who had smoked fewer than 5 cigarettes in total; No contraindications to MRI scan, no history of neuropsychiatric diseases, head trauma, seizures, etc., and no drugs were taken during the experiment. Before the experiment began, each participant signed an informed consent form.
Exclusion criteria
Exclusion criteria: Subject exclusion criteria: (1) mental illness or family history of mental illness; (2) Acute or chronic diseases, including heart and vascular diseases, respiratory diseases, endocrine system diseases, etc.; (3) A metal implant in the head and a pacemaker in the body; (4) Ears with hearing AIDS; (5) common infectious diseases, including hepatitis, AIDS, tuberculosis, etc.; (6) Epilepsy or history of epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fagerstrom Test Nicotine Dependence;Tiffney Questionnaire on Smoking Urges;BOLD fMRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive and negative life events scale;Depression scale; | — |
Countries
China
Contacts
Public ContactDong Guangheng
Hangzhou Normal University
Outcome results
None listed