feeding intolerance in very preterm infants
Conditions
Interventions
observation group:Oral lactase
control group:none
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 0.1 Years
Inclusion criteria
Inclusion criteria: 1. Very preterm infants with gestational age of 28 to 31+6 weeks, regardless of gender; 2. Nutritional enteral feeding (>15ml/kg/d) has begun; 3. The legal guardian agreed to participate in this clinical study and voluntarily signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe congenital malformations such as digestive tract malformations or 1 min Apgar score <= 7; 2. Hypereosinophilia in the blood, accompanied by symptoms of milk protein allergy, such as rash, blood in the stool; 3. Children diagnosed with neonatal necrotizing enterocolitis (NEC) stage IIb and above; 4. The legal guardian is unwilling to sign the informed consent; 5. Discontinue treatment.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| The number of days on which full enteral feeding was achieved;Albumin value;hospital stay;Growth and development indicators; | — |
Primary
| Measure | Time frame |
|---|---|
| Incidence of feeding intolerance; | — |
Countries
China
Contacts
Public ContactChen Jingjing
Peking University Shenzhen Hospital
Outcome results
None listed