Helicobacter pylori-associate gastritis
Conditions
Interventions
Experimental group:Huajuhong powder
Sponsors
Guangzhou University of Chinese Medicine First Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 years old = Age = 65 years old; 2. Confirmed Hp infection by urea breath test; 3. Meets the diagnostic criteria for chronic non-atrophic gastritis according to the "Primary Care Guidelines for Chronic Gastritis (Practical Edition · 2019)"; 4. Diagnosed with dyspepsia and damp-heat pattern in spleen and stomach according to Traditional Chinese Medicine; 5. Upper abdominal distension VAS score > 4 points; 6. Subjects voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who have used antibiotics, bismuth preparations, or PPIs or H2 receptor antagonists within 2 weeks before treatment, or 4 weeks before treatment. 2. Patients with moderate to severe atrophic gastritis, intestinal metaplasia, peptic ulcer, gastric cancer, esophageal cancer, gastric bleeding, biliary, pancreatic, or other serious digestive system diseases. 3. Patients with known allergy to any components in the study drug. 4. Patients with other cancers, malignant tumors, or serious primary diseases of the heart, brain, blood vessels, liver, kidneys, and hematopoietic system. 5. Patients planning to take corticosteroids or non-steroidal anti-inflammatory drugs for a long term. 6. Pregnant, planning to become pregnant, or breastfeeding women. 7. Patients who have participated in other clinical trials within the past 3 months. 8. Patients suspected of alcohol or drug abuse or those deemed unsuitable for this study by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of subjects with Hp (-) after 4 weeks of drug discontinuation; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score for upper abdominal distension;Clinical symptom score;The proportion of subjects with HP(-);The HP test value; | — |
Countries
China
Contacts
Public ContactLi Peiwu
Guangzhou University of Chinese Medicine First Affiliated Hospital
Outcome results
None listed