A prospective study on the effect of acetaminophen mannitol injection on postoperative rehabilitation quality in patients with gastrointestinal tumors

Prospective study on the effect of different analgesia programs on postoperative rehabilitation quality of patients with gastrointestinal tumors - Effect of different analgesia programs on postoperative rehabilitation quality of patients with gastrointestinal tumors

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300076213

Enrollment

Unknown

Registered

2023-09-27

Start date

2023-10-01

Completion date

Unknown

Last updated

2023-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastroenteric tumor

Interventions

treatment group:Acetaminophen mannitol injection 50 ml was injected intravenously after general anesthesia induction/before skin resection, and fentanyl injection 0.1 mg+ acetaminophen mannitol inject

control group:After induction of general anesthesia/before incision, 50 ml of normal saline was injected intravenously, and 0.1 mg of fentanyl + 50 ml of normal saline was injected intravenously 30 mi

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? =18 years old, ASA grade I~III; (2) To perform open/laparoscopic surgery for gastric cancer and open/laparoscopic surgery for colorectal cancer under general anesthesia; ? Can sign informed consent; Ability to read and write.

Exclusion criteria

Exclusion criteria: ? Refuse to participate in this experiment; ? Emergency surgery; ? Patients with incomplete data; ? Severe dementia, speech impairment, severe hearing or visual impairment unable to complete the questionnaire; ? Patients with severe cardiopulmonary, liver, and kidney dysfunction before surgery; ? Chronic pain history and long-term use of analgesic and sedative drugs; ? Patients with mental illness and cognitive dysfunction.

Design outcomes

Primary

Measure	Time frame
Ramsay sedation score;Serum IL-6, TNF-a, cystatin C and urinary acetyl-ß-D glucosaminidase (NAG) ;Postoperative NRS score;Postoperative acute pain assessment;	—

Secondary

Measure	Time frame
European Five Dimensional Health Scale;Postoperative pulmonary complications;	—

Countries

China

Contacts

Public ContactTianxiao Liu

The First Affiliated Hospital of Guangxi Medical University

liutxdoctor@qq.com+86 133 1773 6088

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026