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Effect of intrathecal injection of low dose ropivacaine and sufentanil for labor analgesia in combined spinal-epidural block

Effect of intrathecal injection of low dose ropivacaine and sufentanil for labor analgesia in combined spinal-epidural block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300076206
Enrollment
Unknown
Registered
2023-09-27
Start date
2023-09-30
Completion date
Unknown
Last updated
2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

labor pain

Interventions

EA group:When the cervical orifice was dilated to 2-4 cm, EA was used for labor analgesia
DPE group:When the cervical orifice was dilated to 2-4 cm, DPE was used for labor analgesia
CSE group:When the cervical orifice was dilated to 2-4 cm, CSE was used for labor analgesia

Sponsors

Maternal and Child Health Hospital of Anhui Province
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 36 Years

Inclusion criteria

Inclusion criteria: 1. Term (37-41 gestational weeks); 2. Singleton pregnancy; 3. Aged 20-36 years old; 4. BMI 21.0-35.0 kg/m2; 5. ASA grade I or II.

Exclusion criteria

Exclusion criteria: 1. Contraindications of spinal anesthesia; 2. Known fetal malposition or abnormal birth canal conditions; 3. Known fetal abnormalities; 4. Pregnancy complications (high-risk pregnancies such as severe preeclampsia, placental abruption and placenta previa); 5. History of chronic pain; 6. Prenatal use of psychotropic drugs or poor cooperation with mental disorders; 7. Allergic history to opioid, ester or amide local anesthetics.

Design outcomes

Primary

MeasureTime frame
Incidence of breakthrough pain;

Secondary

MeasureTime frame
Analgesia onset time;VAS score;Bromage score;FHR;MAP;Frequency of contractions;VAS score at 15min after analgesia;Rate of cervical dilation;Maternal satisfaction;Duration of labor;delivery mode;Neonatal outcome;adverse reaction;

Countries

China

Contacts

Public ContactJi Tianzhen

Maternal and Child Health Hospital of Anhui Province

happy_tianzhen@126.com+86 152 5655 0911

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026